Molecular biology Essay Example | Topics and Well Written Essays - 3000 words

Molecular biology - Essay Example (Unemo & Nicholas, 2012). The developing multi drug resistant Neisseria gonorrhoeae, the severe symptoms of the gonococcal infections, added to the socioeconomic burden and epidemiologically threatening aspects of the disease; drug resistance gonorrhea, its detection and diagnosis has acquired immense significance (Blomquist, et al., 2014). It is important to focus on preventing the spread of resistant forms as part of disease management. An essential requirement for controlling spread is enhancing surveillance through better diagnostic methods for identification and isolation of disease resistant pathogens. This project aims to introduce a novel method of diagnosis of drug resistance in clinical isolates of gonorrhea. The method presented in this paper involves the use of Tiling array for diagnosis of drug resistance in clinical isolates of Neisseria gonorrhoeae. The protocol is based on similar technology already used for development of protocols for drug resistance in other organisms. Tiling array is a derivation of microarray technology developed by Kapranov and colleagues (2002) and Shoemaker and colleagues (2001) that facilitates identification of previously unidentified transcripts through genome wide annotations. The initial euphoria associated with the utility and significance of antibacterial and antimicrobial drugs seems to fade with the rise in the bacterial strains exhibiting resistance to single as well as multiple drugs. Hence drug resistance has become an exponentially rising global health hazard rendering world population once again vulnerable to the threats of common diseases (Levy & Marshall, 2004). Both Gram positive and Gram negative bacteria have been known to exhibit multi-drug resistance leaving health care providers with no antimicrobial therapeutic agents ensuring control and management of

Social Learning Theory Essay Example for Free

Social Learning Theory Essay Moral development is successfully achieved when it starts at the youngest learning stage. Vision, character and competence are the three prime elements that a young person needs to develop to achieve moral standards. Moral development of character is an organic process. The integration of an individual’s physical, emotional, spiritual and psychological well-being must be prioritized so that the young human being may be able to achieve moral standards set by his society. It is in this context where social learning theory is able to explain moral development. Learning can occur when a person integrates and relates to his wider social context. People learn from people by observing, imitating and modeling. The principles of social learning theory posit that; People learn while observing other people; Learning through observing social interactions may not necessarily create change in behavior; Social learning is highly cognitive. Observing the effects of behavior of people brings to the individual increased level of awareness on the consequences that behavior might lead to; Social learning has transitory abilities to bridge behaviorist learning theories and cognitive learning theories. Behavior is reinforced by the modeling process as a person adjusts his behavior according to the like and dislikes of the group he wants to be accepted into. By imitating the persons or group of people in the way they speak or the way they dress up, the individual will be successful in getting accepted to be part of the group. In this way, social learning helps the individual attain his desires to be one with the group of his choice. â€Å"Many behaviors can be learned, at least partly, through modeling. Examples that can be cited are, students can watch parents read, students can watch the demonstrations of mathematics problems, or seen someone acting bravely and a fearful situation. Aggression can be learned through models. Much research indicates that children become more aggressive when they observed aggressive or violent models. Moral thinking and moral behavior are influenced by observation and modeling. This includes moral judgments regarding right and wrong that can in part, develop through modeling.† (Ormrod, 1999) Social learning hastens moral development. As an individual observers the environment from which he learns from, his character may be able to imbibe behaviors that help develop moral ways such as engaging in morally relevant conduct or words, or refraining from certain conduct or words (Wynne Walberg, 1984). The individual can also acquire a complex set of relatively persistent qualities of the individual person, and generally, a positive connotation when used in discussions of moral education (Pritchard, 1988). Learning experiences can influence moral behavior development by direct tuition and by observational learning. Direct intuition uses reward and punishment in negating or reaffirming the behavior of an individual. Observational learning is more indirect in nature because the reward and punishment is observed by the individual rather than experienced first hand. When an individual sees his elders being punished for doing bad things such as stealing or murder, it will be engrained in his moral standards that stealing and murder is not morally accepted. Campbell and Bond (1982) propose the following as major factors in the moral development and behavior of youth in contemporary America: heredity, early childhood experience, modeling by important adults and older youth, peer influence, the general physical and social environment, the communications media, what is taught in the schools and other institutions, specific situations and roles that elicit corresponding behavior. And much of these elements are found in the social context therefore social learning theory is a very effective means of how an individual can acquire his or her moral standards just by observing, imitating and modeling his environment. To successfully model moral behavior, a person goes through four learning processes under social learning theory. Attention is the first important process that one has to render. Without the ability of a person to pay attention to himself, and his surroundings learning will be hard. Retention is the next process after attention is achieved. Remembering the observations is essential so that the learning can be further processed. A person who cannot remember his observations will render his social milieu unimportant. Reproducing the remembered observation is crucial in the learning process. Replicating the observed behavior will determine if the individual has truly learned and has truly understood and acquired the moral concept of the situation observed. And finally, there is need for motivation if an individual is bent on succeeding modeling the observed behavior. Motivation will be the key ingredient for the individual to project the learning he has achieved, successfully sharing his perception so that other may be able to observe his actions. With other people observing his actions, the learning process is replicated over and over again. With this replication through the social learning theory, moral development is achieved by the individual and by the whole group. Knowing how social learning can affect moral development, it is important therefore that young people are able to grow up in a moral environment from where they will use their observation skills and imitate or model the actions they see, hear and feel. Moral development starts at an early stage in a child and therefore, society must not be mindless of the moral and immoral actions found in and around the child’s environment. References: Campbell, V., Bond, R. (1982). Evaluation of a character education curriculum. In D. McClelland (ed.), Education for values. New York: Irvington Publishers. Huitt, W. (2004). Moral and character development. Educational Psychology Interactive. Valdosta, GA: Valdosta State University. Retrieved [November 17, 2006], from http://chiron.valdosta.edu/whuitt/col/morchr/morchr.html Moshman, David. 2004.   Adolescent Psychological Development: Rationality, Morality, and Identity. Lawrence Erlbaum Associates; 2nd edition Ormrod, J.E. (1999). Human learning (3rd ed.). Upper Saddle River, NJ: Prentice-Hall. Pritchard, I. (1988). Character education: Research prospects and problems. American Journal of Education, 96(4), 469-495. Rotter, J. B. (1993). Expectancies. In C. E. Walker (Ed.), The history of clinical psychology in autobiography (vol. II) (pp. 273-284). Pacific Grove, CA: Brooks/Cole. Wynne, E., Walberg, H. (Eds.). (1984). Developing character: Transmitting knowledge. Posen, IL: ARL.

Keats and the Senses of Being: Ode on a Grecian Urn (Stanza V) Essay

Keats and the Senses of Being: "Ode on a Grecian Urn" (Stanza V) ABSTRACT: With its focus on the pathos of permanence versus temporality as human aporia and on the function — the Werksein — of the work of art genuinely encountered, John Keats’s Ode on a Grecian Urn is a particularly compelling subject for philosophical analysis. The major explications of this most contentiously debated ode in the language have largely focused, however, on various combinations of the poem’s stylistic, structural, linguistic, psychological, aesthetic, historical, symbolic, and intellectual-biographical elements. My paper articulates a bona fide philosophical approach to the ode’s famously controversial fifth stanza (the one containing the Urn’s declaration: "Beauty is truth, truth beauty"). I demonstrate how William Desmond’s metaphysics of Being-specifically his analysis of the univocal, equivocal, dialectical, and metaxological senses of being-affords the groundwork for a "hermeneutics of the between" that elucidate s the ode’s culminating stanza with all of the cogency and nuance that one would expect to derive from a systematic ontology. In what ways are philosophy and literature mutually elucidating? More specifically, how can a systematic metaphysics serve as a vehicle of insight into the way that literary art renders, in solution as it were, ontological truths that orchestrate our experience of the ideal? I’d like briefly to address these questions by considering the concluding stanza of John Keats’s "Ode on a Grecian Urn" in terms of four complementary ontological keys. These four senses of being — the univocal, the equivocal, the dialectical, and the metaxological—are the heart of a compelling ontology detailed by William Desmond in... ...n the unformed, undifferentiated, prelinguistic word [that] leaves the Du free and stands together with it in reserve where the spirit does not manifest itself but is. (I and Thou 89). Bibliography Buber, Martin. I and Thou. Trans. Walter Kaufmann. New York: Scribners, 1970. Desmond, William. Being and the Between. Albany: SUNY P, 1995. Heidegger, Martin. "The Origin of the Work of Art." Poetry, Language, Thought. Trans. Albert Hofstadter. New York: Harper, 1975. Keats, John. The Complete Poems. Ed. John Barnard. 3rd ed. London: Penguin, 1988. Stambovsky, Phillip. The Depictive Image: Metaphor and Literary Experience. Amherst, MA: U of Massachusetts P, 1988. ——— Myth and the Limits of Reason. Amsterdam and Atlanta: Rodopi, 1996. Stillinger, Jack, ed. Twentieth Century Interpretations of Keats’s Odes. Englewood Cliffs, NJ: Prentice-Hall, 1968.

Obeying a Lawful Order

Army value â€Å"DUTY† In this essay you will learn about one of the most important Army value â€Å"Duty†. In this essay i will be talking about a few diffrent topics that correnspond with the Army value â€Å"Duty†. In this essy you read 3 diffrent stories about how soldiers did there duty and then i will give you 3 stories on how not doing your duty as soldier affects the team. You will also read about leadership duty and how it can either help the lower enlisted or break the lower enlisted. So be prepeared to get some knowledge dropped on and also to learn how you as a leader should think about how it affects joe. Story 1: this story is about a young soldier who was some what squared away. He has been in the army for almost 2 years. During this time in the army he has been smoked, negitived couseled, and even a article 15. So this soldier has been slammed but he didnt get discouraged he kept his head up rolled with the punches and realized he dont have to stay in the army. So where does this story fit in? I know you are asking yourself this question as you read this essay well im about to explian it to you. Okay now back to the story, the soldier was three months away from his ets date and he was happy, excited, shit he even stop showing up for pt, and he had some celebration marry Jane. So this soldier was content on getting out because he felt that the army was not him and it was best to part there ways. So he's a week out and september 11 happens so he runs to the rention officer and reinlist because he knows that it was war time and it wasnt about just hime and his feeling about the army. His counrty was attacked and he took and oath to protect it so he put his personal feeling aside yeah he could have easly hit the yellow brick road, and chucked up the duces as he skipped his happy ass down the road. But he did beleave strongly about the army values and he had to preform his duty as soldier and an american. So this story 1 hold all questions comments and concerns untill i finish. Story 2: This story is about a medal of honor winner. The winner iof this award was in special forces his son is a good friend of sargent o'b. This guy was bad ass he was awared 8 purple hearts two bronze stars with valor and the two bronze stars was orginally metal of honor nominations but was down graded because the mission they accured on was top secert and couldnt be exposed. So the day he recieved his metal of honor he was on a mission and they were pinned down and he recieved the message over the radio that he one the medal of honor some say who ever gave him that message should be shot because he was in a damn fire fight butafter recieving the message he was wounded and that is how he recieved his 8th purple heart. The story of how he recieved his perstigeous award goes like this. Col howard johnson was on a mission his whole team was wounded or dead he was also wounded by a grenade which blew his intestants out he packed his intestants back in his stomach and was holding it in with his left hand, as he was doing this he started to carry out his wounded battle buddies so they can get medivaced he got all of them to the LZ before the birds got there help load them and was the last damn soldier to get on the bird now that takes major guts and all the army values and more. Story 3: â€Å"This story about a soldier who was not honorably discharged from the army. with a little bit of research shows that he was a failure who could not hack the military even in a real echelon slot, and he was booted from the Army for smoking pot after unsuccessfully attempting to get an early discharge. So he didn’t honorably do his duty and earn our respect like his unwashed peers would claim. And his Other Than Honorable Discharge is probably why he’s claiming to be homeless (while jetting to Washington DC from his home in Alaska) instead of using the GI benefits that every honorably discharged vet is entitled to and finding a job or going to school. This soldier is now homeless and is seeking help. â€Å"-(resource new paper article) I know personally that we make mistakes. Even though we make mistakes that does not give society the right to peg us as useless, dirtbags, and all other word they use for so called bad soldiers. t takes alot of guts to join the army durning the time of war and sometimes you make mistakes no matter how big the mistake is we are still human and we make human errors. I belieave in god and i know for a fact that we are not perfect and god forgives us for not being perfect. So take a second and think before you label a soldier a dirtbag and try to help that soldier get over the fence, we are all brothers in arms and we have to take care o f each other. Story 4: This is a story about a soldier who did not for fill his duty in the Army.

Uol Past Year Paper

This paper is not to be removed from the Examination Halls UNIVERSITY OF LONDON AC3093 ZB (279 0093) BSc Degrees and Diplomas for Graduates in Economics, Management, Finance and the Social Sciences, the Diplomas in Economics and Social Sciences and Access Route Auditing and Assurance Friday, 18 May 2012 : 10. 00am to 1. 00pm Candidates should answer FOUR of the following EIGHT questions: TWO from Section A, ONE from Section B and ONE further question from either section. All questions carry equal marks.  © University of London 2012 UL12/0010 D01 PLEASE TURN OVER Page 1 of 6SECTION A Answer TWO questions from this section and not more than one further question. (You are reminded that four questions in total are to be attempted with at least one from Section B. ) 1. You have just been approached by the newly-appointed Senior Regulator for the financial services (including accounting and auditing) industry in a country which has previously had little or no regulation on the provision of financial information. The Regulator has said that his first priority is to improve the quality of annual financial statements which the major companies in the country publish.The Regulator has established working parties to examine improvements in the quality of accounting and financial reporting practices. Another working party has been established to examine the quality of audit field work. The Regulator tells you that he wants your working party to put forward proposals which will improve the quality of audit reporting. He is concerned that present practices allow individual auditors to report in their own way. This has led to confusion, since there are so many different styles of audit report. The Regulator believes that a standardised approach will reduce this confusion.He is aware that there are international auditing standards on auditing and asks you to examine the possibility of adopting an approach consistent with the international standards. He asks you to look at the following specific aspects of audit reporting: †¢ To whom the audit report is addressed †¢ A reference to the framework of accounting †¢ A reference to the framework of auditing †¢ Some discussion of what can be and what cannot be expected from an audit †¢ The style of opinion on the financial statements, and †¢ Any other issues you think might be relevant.Required (a) (b) Draft a report from your working party on the specific issues mentioned above. (15 marks) Draft an appendix to this report setting out the advantages and disadvantages of a standardised approach to audit reporting. (10 marks) UL12/0010 D01 Page 2 of 6 2. You are the audit partner of Lottolife, a leisure establishment which includes a bar and a restaurant open to the general public. The management consists of a senior manager and three assistant managers; all four are paid a salary with a profit-related bonus.Both the bar and the restaurant are dependent on casual workers who are paid an hourly rate in cash at the end of the week. To record the hours worked, each employee has to ‘clock in and clock out’ using a clock card inserted into a machine which records the time in and out. There is no other check on the accuracy of the recorded hours. Workers are hired after a short interview by one of the assistant managers who completes a form to record the details of the successful applicant. The company has a poor reputation as an employer and expects its staff to work long hours.Consequently employees tend not to stay very long. On resigning, an employee has to sign a form which is endorsed by the assistant manager and is then handed to the Payroll Department so that the employee’s last pay packet can be made up and the employee taken off the payroll. There are never enough applicants to fill the vacancies and almost no applicant is rejected. Both pay and staff morale are low. In an attempt to boost the pay and attract more and better staff, one o f the assistant managers has suggested paying a weekly bonus from the cash tips left by customers.The tips would be divided among the workers rather than being banked as part of the takings. There would be no record kept of the tips which would mean that the workers would not be taxed on their ‘bonus’. It also has a members-only club which is a licensed casino where various forms of gambling take place. Under the licensing rules only trained staff can be employed and these are reasonably well paid jobs. Occasionally if there is a staff shortage on the catering side in the casino, members of the bar and restaurant staff are brought in, given new uniforms and are instructed to help out.Technically this is against the gaming rules, but the casino management consider that if the breach is ever discovered by the authorities, the worst thing that might happen would be the casino having to pay a fine. They are aware however that it is possible that the licence could be withdra wn and the casino could be forced to close. Required (a) (b) Identify possible weaknesses in the control environment in Lottolife. (15 marks) Suggest various audit procedures which might be appropriate in the particular circumstances of Lottolife. (10 marks) UL12/0010 D01 Page 3 of 6 3.You have just been appointed auditor of Bruton’s Ltd, a small family-owned gentlemen’s tailors and clothes shop. It is based in the South-West of England where it has six shops in different towns. The clothes it stocks and sells are at the upper end of the price range, appealing to the wealthier customer. The company, like its customers is old-fashioned. In fact, the decor of the shops has not changed since the 1960s. The head of the family and major shareholder, John Bruton, is aged 86 and sees no reason to change what has for fifty years been a winning formula – a top quality service and a premium price.He dismisses the falling sales and lower profits as simply consequences of t he tough economic climate. The three other shareholders are Bruton’s sons, the youngest of whom is 53. The sons have tried to get their father to change strategy since they have seen similar companies in other regions increase their market share through the internet and through a radical make-over of their retail outlets. They accept that their plans will cost about ? 10m and they will need a bank loan to finance what is effectively a re-branding exercise.They believe, though they have not done a detailed analysis, that internet sales over the next three years would bring in enough cash to repay the loan and enough profit to cover loan interest. After that, there would be clear profit for about ten years until the next rebranding was needed. In addition, the leases on the shops are all going to expire in the next five years. These can be renewed but it will be costly as the premises are all in city centre locations which are highly sought after by companies in the food and dr inks industry.With insufficient cash reserves, Bruton’s would need further bank financing to cover the capital cost of renewing these long term leases. The sons are also urging their father to consider buying in cheaper clothes imported from Asia as way of boosting sales and profits. The father who is very patriotic has rejected this suggestion, choosing instead to stay with British-based suppliers who have served him well since he began in business. Bruton’s accounting system dates from the 1960s. It is mainly manual with sales staff making out a handwritten receipt for each sale.Cash is put through a till but there is no reconciliation of receipts and takings through the till. The shops do have credit card facilities but again there is no reconciliation of sales and card receipts. The main element of control is the presence of one of Bruton’s sons. Each is responsible for two shops which they attend on alternate days. This close supervision has seemed to work well until, Roger, the eldest son, had a heart attack and was unable to work for six months. During this time, his two brothers supervised the six shops visiting one every three days.Roger is now back at work though he only works reduced hours at one location. Required (a) (b) Identify the major elements of audit risk in Bruton’s Ltd. (15 marks) Explain the steps you would have taken before formally accepting appointment as auditor of Bruton’s Ltd. (10 marks) UL12/0010 D01 Page 4 of 6 4. You have just been appointed the Quality Assurance Partner in Raiffes & Co. , Chartered Accountants and Registered Auditors. You are currently reviewing a sample of the audit files of five audit clients.Your aim is to ensure that the quality of audit work at least matches and, if possible, exceeds the minimum standard required under the international auditing standards and UK legislation. You have made the following list of items which cause you concern: †¢ In Albany Ltd, the audi t team noted that although accurate inventory records had not been kept during the year, the year-end stock count was tightly controlled and a detailed review of gross profit margins suggested little chance of material error. On this basis the audit manager had recommended signing an unmodified opinion.In Boverton plc, a weakness in internal control had been detected early in the audit. The weakness concerned payroll and may have allowed overpayments to genuine staff and/or payments to fictitious staff. Because payroll is such a sensitive area, the audit team had done nothing more than note the weakness in the audit file, highlighting the issue for partner review. In Chirley plc, the company had failed to comply with the relevant financial reporting standard for pension costs. The matter is one of disclosure rather than measurement.The Finance Director simply will not accept that the standard is correct and insists that he is right. The recommendation from the audit team is to agree with the Finance Director since the accounting numbers are right and the firm should not risk upsetting a major client. In Dalton, a fraud involving the cashier had been discovered. The amount involved was immaterial to the financial statements. When the Finance Director was told about the fraud, he was unmoved, claiming that he knew about the fraud which had been going on since the man was first employed five years ago.The Finance Director said that he allowed the cashier to supplement his salary in this way since it was cheaper than giving him a pay rise. In Exeter Ltd, this was the first year of the audit appointment. The fixed asset register had not been maintained for the last five years meaning that it was impossible to assess from the records how long the assets had been in use. Total tangible fixed assets are material to the financial statements. The team had immediately stopped work on fixed assets concluding that the audit report would have to be modified on the grounds o f disagreement. †¢ †¢ †¢ Required (a) Evaluate the situation in each of the five cases and suggest an appropriate course of action in each including if necessary modifying the auditors’ report. (15 marks) Suggest steps which the firm should take to ensure that all its audits come up tot the appropriate standard. (10 marks) (b) UL12/0010 D01 Page 5 of 6 SECTION B Answer ONE question from this section and not more than one further question. (You are reminded that four questions in total are to be attempted with at least two from Section A. ) 5.Because audit time is not unlimited, sampling is a key component of any audit strategy. Explain the various factors which auditors consider when setting up their sampling plan. 6. Critically evaluate the purpose of an audit from the point of view of the readers of the auditors’ report. 7. You are required to write a general theory of auditing of financial statements. What concepts and assumptions would you include an d what purpose would each serve? 8. Critically evaluate the measures taken in the IFAC Code of Ethics to safeguard auditor independence. END OF PAPER UL12/0010 D01 Page 6 of 6